Post by roberts on Mar 20, 2015 15:15:42 GMT
Dear all,
I am using the --grm-adj option to manipulate my GRM. In the manual it says "input 0 if you assume that the causal loci have similar distribution of allele frequencies as the genotyped SNPs". What if I don't want to assume that? If I for example want to assume that the allele frequencies of the causal loci are lower than in the genotyped SNPs, how can I do that. How does this option work?
Greatful for help!
I am using the --grm-adj option to manipulate my GRM. In the manual it says "input 0 if you assume that the causal loci have similar distribution of allele frequencies as the genotyped SNPs". What if I don't want to assume that? If I for example want to assume that the allele frequencies of the causal loci are lower than in the genotyped SNPs, how can I do that. How does this option work?
Greatful for help!