hku
New Member
Posts: 1
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Post by hku on Jul 25, 2014 21:55:38 GMT
Hello,
I am wondering if principal components or other covariates (gender, age, …) need to be included when using -reml for heritability estimation. I have a data with about 800 individuals and 180k SNPs, but the estimate heritability is 0 with se 0.1. Any suggestion will be helpful. Thanks a lot.
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Post by Jian Yang on Jul 31, 2014 12:04:34 GMT
Yes, I would adjust for covariates for the trait. The sample size is too small. May check spark.rstudio.com/ctgg/gctaPower/for the sample size required to achieve sufficient power.
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