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Is it possible for genetic correlation to be lower because..

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jy New Member Posts: 7	Is it possible for genetic correlation to be lower because.. Mar 26, 2014 4:11:37 GMT Quote Select Post Deselect Post Link to Post Member Give Gift Back to Top Post by jy on Mar 26, 2014 4:11:37 GMT ...the ratio of case sample size to control sample size is low. In other words, does a small case sample size compared to control sample size lead to lower genetic correlation? Thanks!

Jian Yang
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Is it possible for genetic correlation to be lower because.. Mar 26, 2014 11:22:27 GMT

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Post by Jian Yang on Mar 26, 2014 11:22:27 GMT

rG won't be dependent of sample size but the SE of the estimate of rG will. If the sample size is too small, the estimate will fluctuate a lot so that any increase or decrease of the estimate would just be noise (sampling error).