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Covariance between SMR betas estimated at two SNPs in LD

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Daniel_04
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Covariance between SMR betas estimated at two SNPs in LD May 15, 2020 7:40:57 GMT

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Post by Daniel_04 on May 15, 2020 7:40:57 GMT

Hello,

Sorry if this is a very beginner's question, but in the formula to obtain the sampling covariance between SMR betas estimated at two SNPs in LD, is the LD correlation measure used r or r2?

Thanks,

Daniel

ax New Member Posts: 27	Covariance between SMR betas estimated at two SNPs in LD Jun 22, 2020 11:10:05 GMT Quote Select Post Deselect Post Link to Post Member Give Gift Back to Top Post by ax on Jun 22, 2020 11:10:05 GMT Hi Daniel, Are you referring to the equation (9) in the SMR paper? If so, the LD correlation measure used is r. Cheers, Angli

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