Post by Jian Yang on Jun 10, 2015 6:09:22 GMT
An alternative to GCTA-GREML analysis.
Example
Output
Results are saved in *.HEreg file.
HE-SD: HE regression using the square difference of the phenotypes for pairwise individuals
HE-CP: HE regression using the cross product the phenotypes for pairwise individuals
Example
gcta64 --HEreg --grm test --pheno test.phen --out testOutput
Results are saved in *.HEreg file.
HE-SD
Coefficient Estimate SE P
Intercept 1.99992 0.00099822 0
Slope -0.31676 0.0145436 3.62279e-105
V(G)/Vp 0.158386 0.00727212
HE-CP
Coefficient Estimate SE P
Intercept -0.000213987 0.00036016 0.552416
Slope 0.158594 0.00524738 1.20002e-200
V(G)/Vp 0.158594 0.00524738HE-SD: HE regression using the square difference of the phenotypes for pairwise individuals
HE-CP: HE regression using the cross product the phenotypes for pairwise individuals