BLUP genetic and residual correlation

new

« Prev
1
Next »

jcole
New Member

Posts: 4

BLUP genetic and residual correlation Oct 20, 2015 15:59:40 GMT

Quote

Post by jcole on Oct 20, 2015 15:59:40 GMT

Hello,

I have used BLUP in --reml-pred-rand to estimate the total genetic effect and residual effect for each individual. I'm finding these values to be highly correlated. It was previously my understanding that there should NOT be correlation between fitted values and residuals in a regression.

Can you please explain why these values might be correlated?

Thank you!

Jian Yang
Administrator

Posts: 362

BLUP genetic and residual correlation Oct 21, 2015 6:00:12 GMT

Quote

Post by Jian Yang on Oct 21, 2015 6:00:12 GMT

Please see gcta.freeforums.net/thread/219/run-gblup-prediction-analysis-gcta

g_hat = V_gA V^-1y and e_hat = V_eV^-1y
where V_g is the genetic variance, V_e is the residual variance, A is the GRM, and y is the phenotype vector.

So, they are highly correlated.

Last Edit: Oct 21, 2015 6:22:45 GMT by Jian Yang