Assumptions for mathematical model of GCTA Jan 26, 2016 16:43:17 GMT Quote Select PostDeselect PostLink to PostMemberGive GiftBack to Top Post by lulipe on Jan 26, 2016 16:43:17 GMT Hi everyone!I would like to do an analysis similar to the one proposed by Zaitlen et al. (2013), estimating narrow-sense heritability and heritability explained by genotyped SNPs with family data from a GWAS.I've already read the relevant publications. Now, I am wondering about the exact assumptions for using GCTA in the above setting:* Residuals and random effects are supposed to be normal. How can you check that?* What about continuous phenotypes... Do they have to be normal as well?I would be really glad to read some words about that as it hasn't been covered either in the FAQ nor in this Forum.Thank you very much in advance!