Post by catarina on Feb 8, 2016 14:13:58 GMT
Hi,
I am attempting to run GCTA for a chromosome partitioning study using related individuals. I am using the new GCTA version with the Zaitlen et al. (2013 PLoS Genetics) method.
However, when I try to run a chromosome partition analysis I get the error: "the information matrix is not invertible".
I am fitting all chromosomes in the model using the 2 GRMs (from all SNPs in a family data set and the additional GRM using --make-bK 0.05)
Does this new method allow for the estimation of variance explained by each chromosome?
Thanks in advance!
Catarina
I am attempting to run GCTA for a chromosome partitioning study using related individuals. I am using the new GCTA version with the Zaitlen et al. (2013 PLoS Genetics) method.
However, when I try to run a chromosome partition analysis I get the error: "the information matrix is not invertible".
I am fitting all chromosomes in the model using the 2 GRMs (from all SNPs in a family data set and the additional GRM using --make-bK 0.05)
Does this new method allow for the estimation of variance explained by each chromosome?
Thanks in advance!
Catarina
