Post by mandar on Jun 19, 2016 2:55:48 GMT
Hello,
It may be a naive question but is the normality of the phenotype necessary for the stability estimate of heritability?
(The reason for asking this question is ; I estimated heritability on bunch of phenotypes; grep results shown below with SE of the estimate. Plots for phenotype distribution attached)
After looking at heritability estimates such as below, for set of 7 serial measurements of the same phenotype; do you have any suggestion about why it may be suddenly dropping heritability estimate to zero?
PS. Serial measures are for glucose from Oral glucose tolerance test over 2 hrs. 1st at baseline 2 nd to last after 75 gm of oral glucose at different time intervals.
V(G)/Vp 0.468111 0.300732
V(G)/Vp 0.000001 0.244915
V(G)/Vp 0.000001 0.222169
V(G)/Vp 0.000001 0.206394
V(G)/Vp 0.000001 0.260440
V(G)/Vp 0.052010 0.213405
Any comments or insights from experienced eyes will be helpful.
Thank you
-Mandar![]()
It may be a naive question but is the normality of the phenotype necessary for the stability estimate of heritability?
(The reason for asking this question is ; I estimated heritability on bunch of phenotypes; grep results shown below with SE of the estimate. Plots for phenotype distribution attached)
After looking at heritability estimates such as below, for set of 7 serial measurements of the same phenotype; do you have any suggestion about why it may be suddenly dropping heritability estimate to zero?
PS. Serial measures are for glucose from Oral glucose tolerance test over 2 hrs. 1st at baseline 2 nd to last after 75 gm of oral glucose at different time intervals.
V(G)/Vp 0.468111 0.300732
V(G)/Vp 0.000001 0.244915
V(G)/Vp 0.000001 0.222169
V(G)/Vp 0.000001 0.206394
V(G)/Vp 0.000001 0.260440
V(G)/Vp 0.052010 0.213405
Any comments or insights from experienced eyes will be helpful.
Thank you
-Mandar
Attachments:
