In the estimation of heritability, the standard deviation of h^2 seems to be related on the sample size. Is it also related to the number of SNPs? If we have a sample size of 1,500 individuals and 500,000 SNPs, the sandard deviation of h^2 is the same as the one estimated with the same sample size and 100,000 SNPs?
Good afternoon, May I ask you a stupid question please? I have build the file *.ma. It looks like a file from your description, but i have an error "Invalid sample size in line". Can you recommend a way for creating .ma files please? Thank you.
I am doing some multivariate fusion analysis with Imaging and genetic data, so our sample sizes are not that large compared to conventional GWAS type approaches. Would it be proper to estimate heritability using GCTA using about 600 subjects and about 20k SNPs?