mila
New Member
Posts: 1
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Post by mila on Jun 24, 2021 14:43:27 GMT
Dear gcta users.
I am new in GCTA and I am trying to make a GWAS analysis using Generalized Linear Mixed Models for a binomial trait.
I want to do a GWAS but indicating the Genomic Relationship Matrix (GRM), namely, similar to a GBLUP method, but in this case using as response variable a binary trait.
I have my inverse GRM that I calculated as the method 2 of VanRaden 2008.
Then, I want to use GCTA but using this inverse GRM and do a GWAS analysis for this binary trait.
Could you, please, help me in creating a GCTA script for this analysis?
Many thanks.
Mila
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