Post by sjwidmay on Feb 28, 2022 23:18:45 GMT
Hi there!
I've found a lot of success performing GWAS in populations of my model organism of interest by using the kinship matrix constructed using the --make-grm-inbred flag.
Could someone point me to a paper/more detailed documentation on exactly how this kinship matrix is constructed for inbred populations, as opposed to the default kinship matrix construction algorithm? I'd like to learn about the advantages this algorithm is clearly providing for my application.
Thanks!
Sam
I've found a lot of success performing GWAS in populations of my model organism of interest by using the kinship matrix constructed using the --make-grm-inbred flag.
Could someone point me to a paper/more detailed documentation on exactly how this kinship matrix is constructed for inbred populations, as opposed to the default kinship matrix construction algorithm? I'd like to learn about the advantages this algorithm is clearly providing for my application.
Thanks!
Sam